Calmare- Contraindications & Medications

Calmare is an advanced electrical stimulation treatment. Therefore the following should not receive Calmare Therapy:

  • pacemaker or automatic defibrillator
  • spinal cord stimulator or other implanted pain stimulator operational or non operational
  • aneurysm clip, vena cava clips, or skull plates (metal implants ofr orthopedic repair such as pins, plates and joint replacements are allowed)
  • pregnant and/or breastfeeding
  • history of epilepsy, brain damage, use of anti-convulsants other than pain control
  • prior celiac plexus block, or other neurolytic pain control treatment within 4 weeks
  • wounds or skin irritation in areas where the electrodes are to be placed
  • history of, or have been treated for myocardial infarction or ischemic heart disease within the past six months
  • severe arrhythmia or any form off equivalent heart disease
  • implanted drug delivery system
  • active withdrawal from drugs and/or alcohol
  • previous intolerance to transcutaneous electronic nerve stimulation
  • you are on neuroleptic medications (examples: carbamazepine, pregabalin, gabapentin) which appear to interfere with treatment efficacy and decrease longevity of no-pain post treatment protocol (these must be weaned prior)

The following conditions should be considered as Precautions to receiving Calmare Therapy:

  • You have pain originating in the central nervous system
  • stimulation over the neck (laryngeal and pharyngeal) due to muscle contraction may be strong enough to close the airway or cause difficulty breathing
  • because this device is capable of delivering a charge per pulse of 25 coulombs or greater, electrodes should not be placed in a trans-thoracic position (may cause arrhythmia)
  • you are prone to skin irritation (isolated cases have occurred)
  • you have no clear diagnosis of neuropathic pain
  • you are connected to other electronic monitoring equipment (ECG monitor). Calmare may not operate properly with the medical device in use


There are medications which do not cooperate with Calmare. They should be titred with the advice of you physician prior to beginning Calmare as they will render Calmare less effective.